A carregar...
O-GlcNAc on NOTCH1 EGF repeats regulates ligand-induced Notch signaling and vascular development in mammals
The glycosyltransferase EOGT transfers O-GlcNAc to a consensus site in epidermal growth factor-like (EGF) repeats of a limited number of secreted and membrane proteins, including Notch receptors. In EOGT-deficient cells, the binding of DLL1 and DLL4, but not JAG1, canonical Notch ligands was reduced...
Na minha lista:
| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2017
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5388531/ https://ncbi.nlm.nih.gov/pubmed/28395734 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.24419 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|