Structure and Biocatalytic Scope of Coclaurine N‐Methyltransferase

Benzylisoquinoline alkaloids (BIAs) are a structurally diverse family of plant secondary metabolites, which have been exploited to develop analgesics, antibiotics, antitumor agents, and other therapeutic agents. Biosynthesis of BIAs proceeds via a common pathway from tyrosine to (S)‐reticulene at wh...

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Vydáno v:Angew Chem Int Ed Engl
Hlavní autoři: Bennett, Matthew R., Thompson, Mark L., Shepherd, Sarah A., Dunstan, Mark S., Herbert, Abigail J., Smith, Duncan R. M., Cronin, Victoria A., Menon, Binuraj R. K., Levy, Colin, Micklefield, Jason
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
Communications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6099451/
https://ncbi.nlm.nih.gov/pubmed/29791083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201805060
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