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Biocatalytic Parallel Interconnected Dynamic Asymmetric Disproportionation of α‐Substituted Aldehydes: Atom‐Efficient Access to Enantiopure (S)‐Profens and Profenols

The biocatalytic asymmetric disproportionation of aldehydes catalyzed by horse liver alcohol dehydrogenase (HLADH) was assessed in detail on a series of racemic 2‐arylpropanals. Statistical optimization by means of design of experiments (DoE) allowed the identification of critical interdependencies...

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Detalhes bibliográficos
Publicado no:Adv Synth Catal
Main Authors: Tassano, Erika, Faber, Kurt, Hall, Mélanie
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6099231/
https://ncbi.nlm.nih.gov/pubmed/30147639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adsc.201800541
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