Improvement of the Process Stability of Arylmalonate Decarboxylase by Immobilization for Biocatalytic Profen Synthesis

The enzyme arylmalonate decarboxylase (AMDase) enables the selective synthesis of enantiopure (S)-arylpropinates in a simple single-step decarboxylation of dicarboxylic acid precursors. However, the poor enzyme stability with a half-life time of about 1.2 h under process conditions is a serious limi...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Aßmann, Miriam, Mügge, Carolin, Gaßmeyer, Sarah Katharina, Enoki, Junichi, Hilterhaus, Lutz, Kourist, Robert, Liese, Andreas, Kara, Selin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352704/
https://ncbi.nlm.nih.gov/pubmed/28360905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.00448
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