Učitavanje...
Synergistic Effect of Simvastatin and Romidepsin on Gamma-globin Gene Induction
OBJECTIVE: Hemoglobinopathies such as beta-thalassemia and sickle cell disease (SCD) are inherited disorders that are caused by mutations in beta-globin chain. Gamma-globin gene reactivation can ameliorate clinical manifestations of beta- thalassemia and SCD. Drugs that induce fetal hemoglobin (HbF)...
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| Izdano u: | Cell J |
|---|---|
| Glavni autori: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Royan Institute
2019
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6099151/ https://ncbi.nlm.nih.gov/pubmed/30124006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22074/cellj.2019.5589 |
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