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Mild hypoxia and human bone marrow mesenchymal stem cells synergistically enhance expansion and homing capacity of human cord blood CD34+ stem cells

OBJECTIVE(S): Cord blood (CB) is known as a valuable source of hematopoietic stem cells (HSC). Identifying strategies that enhance expansion and maintain engraftment and homing capacity of HSCs can improve transplant efficiency. In this study, we examined different culture conditions on ex vivo expa...

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Bibliographic Details
Published in:Iran J Basic Med Sci
Main Authors: Mohammadali, Fatemeh, Abroun, Saeid, Atashi, Amir
Format: Artigo
Language:Inglês
Published: Mashhad University of Medical Sciences 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6098959/
https://ncbi.nlm.nih.gov/pubmed/30140410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/IJBMS.2018.26820.6561
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