Peptide nucleic acid (PNA) binding-mediated induction of human gamma-globin gene expression.

Peptide nucleic acids (PNAs) can bind to homopurine/homopyrimidine sequences of double-stranded DNA targets in a sequence-specific manner and form [PNA]2/DNA triplexes with single-stranded DNA D-loop structures at the PNA binding sites. These D-loop structures have been found to have a capacity to i...

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Detalhes bibliográficos
Main Authors: Wang, G, Xu, X, Pace, B, Dean, D A, Glazer, P M, Chan, P, Goodman, S R, Shokolenko, I
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC148492/
https://ncbi.nlm.nih.gov/pubmed/10373600
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