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mTOR-dependent phosphorylation controls TFEB nuclear export
During starvation the transcriptional activation of catabolic processes is induced by the nuclear translocation and consequent activation of transcription factor EB (TFEB), a master modulator of autophagy and lysosomal biogenesis. However, how TFEB is inactivated upon nutrient refeeding is currently...
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| Publicado en: | Nat Commun |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6098152/ https://ncbi.nlm.nih.gov/pubmed/30120233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05862-6 |
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