Telomeric Recombination Induced by DNA Damage Results in Telomere Extension and Length Heterogeneity

About 15% of human cancers counteract telomere loss by alternative lengthening of telomeres (ALT), which is attributed to homologous recombination (HR)–mediated events. But how telomeric HR leads to length elongation is poorly understood. Here, we explore telomere clustering and telomeric HR induced...

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Veröffentlicht in:Neoplasia
Hauptverfasser: Liu, Haiying, Xie, Yujie, Zhang, Zepeng, Mao, Pingsu, Liu, Jingfan, Ma, Wenbin, Zhao, Yong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Neoplasia Press 2018
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Original article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6097467/
https://ncbi.nlm.nih.gov/pubmed/30118998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2018.07.004
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