Telomeric Recombination Induced by DNA Damage Results in Telomere Extension and Length Heterogeneity

About 15% of human cancers counteract telomere loss by alternative lengthening of telomeres (ALT), which is attributed to homologous recombination (HR)–mediated events. But how telomeric HR leads to length elongation is poorly understood. Here, we explore telomere clustering and telomeric HR induced...

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Vydáno v:Neoplasia
Hlavní autoři: Liu, Haiying, Xie, Yujie, Zhang, Zepeng, Mao, Pingsu, Liu, Jingfan, Ma, Wenbin, Zhao, Yong
Médium: Artigo
Jazyk:Inglês
Vydáno: Neoplasia Press 2018
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Original article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6097467/
https://ncbi.nlm.nih.gov/pubmed/30118998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2018.07.004
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