Telomeric Recombination Induced by DNA Damage Results in Telomere Extension and Length Heterogeneity

About 15% of human cancers counteract telomere loss by alternative lengthening of telomeres (ALT), which is attributed to homologous recombination (HR)–mediated events. But how telomeric HR leads to length elongation is poorly understood. Here, we explore telomere clustering and telomeric HR induced...

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Detalhes bibliográficos
Publicado no:Neoplasia
Main Authors: Liu, Haiying, Xie, Yujie, Zhang, Zepeng, Mao, Pingsu, Liu, Jingfan, Ma, Wenbin, Zhao, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2018
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Original article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6097467/
https://ncbi.nlm.nih.gov/pubmed/30118998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2018.07.004
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