Study of the antimalarial activity of 4-aminoquinoline compounds against chloroquine-sensitive and chloroquine-resistant parasite strains

This study is concerned with identifying features of 4-aminoquinoline scaffolds that can help pinpoint characteristics that enhance activity against chloroquine-resistant parasites. Statistically valid predictive models are reported for a series of 4-aminoquinoline analogues that are active against...

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Bibliografiska uppgifter
I publikationen:J Mol Model
Huvudupphovsmän: Lawrenson, Alexandre S., Cooper, David L., O’Neill, Paul M., Berry, Neil G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer Berlin Heidelberg 2018
Ämnen:
Original Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6097041/
https://ncbi.nlm.nih.gov/pubmed/30120591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00894-018-3755-z
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