Synthesis and Antimalarial Activity of 4-Methylaminoquinoline Compounds against Drug-Resistant Parasite

[Image: see text] A series of novel 4-aminoquinoline analogues bearing a methyl group at 4-aminoquinoline moiety were synthesized via a new and robust synthetic route comprising in situtert-butoxycarbonyl (Boc) deprotection–methylation cascade resulting in the corresponding N-methylated secondary am...

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Udgivet i:ACS Omega
Main Authors: Tiwari, Vinay Shankar, Joshi, Prince, Yadav, Kanchan, Sharma, Anamika, Chowdhury, Sushobhan, Manhas, Ashan, Kumar, Niti, Tripathi, Renu, Haq, Wahajul
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2021
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8158791/
https://ncbi.nlm.nih.gov/pubmed/34056449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c06053
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