Structural Basis for the Broad, Antibody-Mediated Neutralization of H5N1 Influenza Virus

Human infection with highly pathogenic avian influenza A viruses causes severe disease and fatalities. We previously identified a potent and broadly neutralizing antibody (bnAb), 13D4, against the H5N1 virus. Here, we report the co-crystal structure of 13D4 in complex with the hemagglutinin (HA) of...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Virol
Päätekijät: Lin, Qingshan, Li, Tingting, Chen, Yixin, Lau, Siu-Ying, Wei, Minxi, Zhang, Yuyun, Zhang, Zhenyong, Yao, Qiaobin, Li, Jinjin, Li, Zhihai, Wang, Daning, Zheng, Qingbing, Yu, Hai, Gu, Ying, Zhang, Jun, Chen, Honglin, Li, Shaowei, Xia, Ningshao
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2018
Aiheet:
Structure and Assembly
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096824/
https://ncbi.nlm.nih.gov/pubmed/29925655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00547-18
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