Identification of Broad-Genotype HPV L2 Neutralization Site for Pan-HPV Vaccine Development by a Cross-Neutralizing Antibody

Human Papillomavirus (HPV), a non-enveloped, double-stranded DNA virus, is responsible for 5% of human cancers. The HPV capsid consists of major and minor structural proteins, L1 and L2. L1 proteins form an icosahedral shell with building blocks of the pentameric capsomere, and one L2 molecule exten...

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Detalhes bibliográficos
Publicado no:PLoS One
Principais autores: Wang, Daning, Li, Zhihai, Xiao, Jieqiong, Wang, Junqi, Zhang, Li, Liu, Yajing, Fan, Fei, Xin, Lu, Wei, Minxi, Kong, Zhibo, Yu, Hai, Gu, Ying, Zhang, Jun, Li, Shaowei, Xia, Ningshao
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408011/
https://ncbi.nlm.nih.gov/pubmed/25905781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123944
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