Crystal Structures of Two Immune Complexes Identify Determinants for Viral Infectivity and Type-Specific Neutralization of Human Papillomavirus

Persistent, high-risk human papillomavirus (HPV) infection is the primary cause of cervical cancer. Neutralizing antibodies elicited by L1-only virus-like particles (VLPs) can block HPV infection; however, the lack of high-resolution structures has limited our understanding of the mode of virus infe...

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Detalles Bibliográficos
Publicado en:mBio
Main Authors: Li, Zhihai, Wang, Daning, Gu, Ying, Song, Shuo, He, Maozhou, Shi, Jingjie, Liu, Xinlin, Wei, Shuangping, Li, Jinjin, Yu, Hai, Zheng, Qingbing, Yan, Xiaodong, Baker, Timothy S., Zhang, Jun, McLellan, Jason S., Li, Shaowei, Xia, Ningshao
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2017
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5615192/
https://ncbi.nlm.nih.gov/pubmed/28951471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00787-17
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