Viral neutralization by antibody-imposed physical disruption

In adaptive immunity, organisms produce neutralizing antibodies (nAbs) to eliminate invading pathogens. Here, we explored whether viral neutralization could be attained through the physical disruption of a virus upon nAb binding. We report the neutralization mechanism of a potent nAb 8C11 against th...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Zheng, Qingbing, Jiang, Jie, He, Maozhou, Zheng, Zizheng, Yu, Hai, Li, Tingting, Xue, Wenhui, Tang, Zimin, Ying, Dong, Li, Zekai, Song, Shuo, Liu, Xinlin, Wang, Kaihang, Zhang, Zhiqing, Wang, Daning, Wang, Yingbin, Yan, Xiaodong, Zhao, Qinjian, Zhang, Jun, Gu, Ying, Li, Shaowei, Xia, Ningshao
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6936700/
https://ncbi.nlm.nih.gov/pubmed/31818956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1916028116
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