Structural Basis for the Shared Neutralization Mechanism of Three Classes of Human Papillomavirus Type 58 Antibodies with Disparate Modes of Binding

Human papillomavirus type 58 (HPV58) is associated with cervical cancer and poses a significant health burden worldwide. Although the commercial 9-valent HPV vaccine covers HPV58, the structural and molecular-level neutralization sites of the HPV58 complete virion are not fully understood. Here, we...

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Publicado en:J Virol
Autores principales: He, Maozhou, Chi, Xin, Zha, Zhenghui, Li, Yunbing, Chen, Jie, Huang, Yang, Huang, Shiwen, Yu, Miao, Wang, Zhiping, Song, Shuo, Liu, Xinlin, Wei, Shuangping, Li, Zekai, Li, Tingting, Wang, Yingbin, Yu, Hai, Zhao, Qinjian, Zhang, Jun, Zheng, Qingbing, Gu, Ying, Li, Shaowei, Xia, Ningshao
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2021
Materias:
Structure and Assembly
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092703/
https://ncbi.nlm.nih.gov/pubmed/33472937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01587-20
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