Properties and Therapeutic Efficacy of Broadly Reactive Chimeric and Humanized H5-Specific Monoclonal Antibodies against H5N1 Influenza Viruses

Highly pathogenic H5N1 virus infection causes severe disease and a high rate of fatality in humans. Development of humanized monoclonal antibodies may provide an efficient therapeutic regime for H5N1 virus infection. In the present study, broadly cross-reactive monoclonal antibodies (MAbs) derived f...

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Bibliografiske detaljer
Main Authors: Zheng, Qingbing, Xia, Lin, Wu, Wai Lan, Zheng, Zhenhua, Huo, Yongting, Wu, Jun, Liu, Yanning, Yu, Hai, Chen, Yixin, Lau, Siu-Ying, Chen, Honglin, Luo, Wenxin, Xia, Ningshao
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2011
Fag:
Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067186/
https://ncbi.nlm.nih.gov/pubmed/21245446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01436-10
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