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The Human Cytomegalovirus Protein UL148A Downregulates the NK Cell-Activating Ligand MICA To Avoid NK Cell Attack

Natural killer (NK) cells are lymphocytes of the innate immune system capable of killing hazardous cells, including virally infected cells. NK cell-mediated killing is triggered by activating receptors. Prominent among these is the activating receptor NKG2D, which binds several stress-induced ligand...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Dassa, Liat, Seidel, Einat, Oiknine-Djian, Esther, Yamin, Rachel, Wolf, Dana G., Le-Trilling, Vu Thuy Khanh, Mandelboim, Ofer
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096798/
https://ncbi.nlm.nih.gov/pubmed/29950412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00162-18
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