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Human cytomegalovirus escapes immune recognition by NK cells through the downregulation of B7-H6 by the viral genes US18 and US20

Human cytomegalovirus (HCMV) is a major human pathogen, causing serious diseases in immunocompromised populations and congenially infected neonates. One of the main immune cells acting against the virus are Natural Killer (NK) cells. Killing by NK cells is mediated by a small family of activating re...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Charpak-Amikam, Yoav, Kubsch, Tobias, Seidel, Einat, Oiknine-Djian, Esther, Cavaletto, Noemi, Yamin, Rachel, Schmiedel, Dominik, Wolf, Dana, Gribaudo, Giorgio, Messerle, Martin, Cicin-Sain, Luka, Mandelboim, Ofer
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561058/
https://ncbi.nlm.nih.gov/pubmed/28819195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08866-2
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