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Quantification of total dinutuximab concentrations in neuroblastoma patients with liquid chromatography tandem mass spectrometry

Neuroblastoma is one of the most commonly found solid tumors in children. The monoclonal antibody dinutuximab (DNX) targets the sialic acid-containing glycosphingolipid GD2 expressed on almost all neuroblastoma tumor cells and induces cell lysis. However, the expression of GD2 is not limited to tumo...

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Detalhes bibliográficos
Publicado no:Anal Bioanal Chem
Main Authors: El Amrani, Mohsin, Szanto, Celina L., Hack, C. Erik, Huitema, Alwin D. R., Nierkens, Stefan, van Maarseveen, Erik M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096702/
https://ncbi.nlm.nih.gov/pubmed/29938370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-018-1198-0
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