Quantification of total dinutuximab concentrations in neuroblastoma patients with liquid chromatography tandem mass spectrometry

Neuroblastoma is one of the most commonly found solid tumors in children. The monoclonal antibody dinutuximab (DNX) targets the sialic acid-containing glycosphingolipid GD2 expressed on almost all neuroblastoma tumor cells and induces cell lysis. However, the expression of GD2 is not limited to tumo...

Full description

Saved in:
Bibliographic Details
Published in:Anal Bioanal Chem
Main Authors: El Amrani, Mohsin, Szanto, Celina L., Hack, C. Erik, Huitema, Alwin D. R., Nierkens, Stefan, van Maarseveen, Erik M.
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2018
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096702/
https://ncbi.nlm.nih.gov/pubmed/29938370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-018-1198-0
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items