Jujuboside A promotes Aβ clearance and ameliorates cognitive deficiency in Alzheimer's disease through activating Axl/HSP90/PPARγ pathway

Rationale: It has been reported that peroxisome proliferator activated receptor γ (PPARγ) level decreases significantly in the brains of Alzheimer's disease (AD) patients and mice models, while the mechanism is unclear. This study aims to unravel the mechanism that amyloid β (Aβ) decreases PPAR...

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Podrobná bibliografie
Vydáno v:Theranostics
Hlavní autoři: Zhang, Mu, Qian, Cheng, Zheng, Zu-Guo, Qian, Fei, Wang, Yanyan, Thu, Pyone Myat, Zhang, Xin, Zhou, Yaping, Tu, Lifan, Liu, Qingling, Li, Hui-Jun, Yang, Hua, Li, Ping, Xu, Xiaojun
Médium: Artigo
Jazyk:Inglês
Vydáno: Ivyspring International Publisher 2018
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096387/
https://ncbi.nlm.nih.gov/pubmed/30128052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.26164
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