Suppression of Cleavage Factor Im 25 Promotes the Proliferation of Lung Cancer Cells through Alternative Polyadenylation

BACKGROUND: Non-small cell lung cancer (NSCLC) is a life-threatening disease that has a poor prognosis and low survival rate. Cleavage factor Im 25 (CFIm25) is a RNA-binding protein that if down-regulated causes 3’UTR shortening and thus promotes the transcript stability of target genes. It is not c...

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Udgivet i:Biochem Biophys Res Commun
Main Authors: Huang, Jingjing, Weng, Tingting, Ko, Junsuk, Chen, Ning-yuan, Xiang, Yu, Volcik, Kelly, Han, Leng, Blackburn, Michael R., Lu, Xiang
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6095800/
https://ncbi.nlm.nih.gov/pubmed/29928883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2018.06.087
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