Nebulization of Single-Chain Tissue-Type and Single-Chain Urokinase Plasminogen Activator for Treatment of Inhalational Smoke-Induced Acute Lung Injury

Single-chain tissue-type plasminogen activator (sctPA) and single-chain urokinase plasminogen activator (scuPA) have attracted interest as enzymes for the treatment of inhalational smoke-induced acute lung injury (ISALI). In this study, the pulmonary delivery of commercial human sctPA and lyophilize...

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Veröffentlicht in:J Drug Deliv Sci Technol
Hauptverfasser: Surasarang, Soraya Hengsawas, Sahakijpijarn, Sawittree, Florova, Galina, Komissarov, Andrey A., Nelson, Christina L., Perenlei, Enkhbaatar, Fukuda, Satoshi, Wolfson, Marla R., Shaffer, Thomas H., Idell, Steven, Williams, Robert O.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6095669/
https://ncbi.nlm.nih.gov/pubmed/30123328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jddst.2018.04.013
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