Perfluorochemical‐facilitated plasminogen activator delivery to the airways: A novel treatment for inhalational smoke‐induced acute lung injury

BACKGROUND: Effective clinical management of airway clot and fibrinous cast formation of severe inhalational smoke‐induced acute lung injury (ISALI) is lacking. Aerosolized delivery of tissue plasminogen activator (tPA) is confounded by airway bleeding; single‐chain urokinase plasminogen activator (...

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Pubblicato in:Clin Transl Med
Autori principali: Wolfson, Marla R., Enkhbaatar, Perenlei, Fukuda, Satoshi, Nelson, Christina L., Williams, Robert O., Surasarang, Soraya Hengsawas, Sahakijpijarn, Sawittree, Calendo, Gennaro, Komissarov, Andrey A., Florova, Galina, Sarva, Krishna, Idell, Steven I., Shaffer, Thomas H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7240845/
https://ncbi.nlm.nih.gov/pubmed/32508014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ctm2.26
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