Perfluorochemical‐facilitated plasminogen activator delivery to the airways: A novel treatment for inhalational smoke‐induced acute lung injury

BACKGROUND: Effective clinical management of airway clot and fibrinous cast formation of severe inhalational smoke‐induced acute lung injury (ISALI) is lacking. Aerosolized delivery of tissue plasminogen activator (tPA) is confounded by airway bleeding; single‐chain urokinase plasminogen activator (...

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Udgivet i:Clin Transl Med
Main Authors: Wolfson, Marla R., Enkhbaatar, Perenlei, Fukuda, Satoshi, Nelson, Christina L., Williams, Robert O., Surasarang, Soraya Hengsawas, Sahakijpijarn, Sawittree, Calendo, Gennaro, Komissarov, Andrey A., Florova, Galina, Sarva, Krishna, Idell, Steven I., Shaffer, Thomas H.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7240845/
https://ncbi.nlm.nih.gov/pubmed/32508014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ctm2.26
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