Perfluorochemical‐facilitated plasminogen activator delivery to the airways: A novel treatment for inhalational smoke‐induced acute lung injury

BACKGROUND: Effective clinical management of airway clot and fibrinous cast formation of severe inhalational smoke‐induced acute lung injury (ISALI) is lacking. Aerosolized delivery of tissue plasminogen activator (tPA) is confounded by airway bleeding; single‐chain urokinase plasminogen activator (...

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Detalhes bibliográficos
Publicado no:Clin Transl Med
Main Authors: Wolfson, Marla R., Enkhbaatar, Perenlei, Fukuda, Satoshi, Nelson, Christina L., Williams, Robert O., Surasarang, Soraya Hengsawas, Sahakijpijarn, Sawittree, Calendo, Gennaro, Komissarov, Andrey A., Florova, Galina, Sarva, Krishna, Idell, Steven I., Shaffer, Thomas H.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7240845/
https://ncbi.nlm.nih.gov/pubmed/32508014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ctm2.26
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