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Perfluorochemical‐facilitated plasminogen activator delivery to the airways: A novel treatment for inhalational smoke‐induced acute lung injury

BACKGROUND: Effective clinical management of airway clot and fibrinous cast formation of severe inhalational smoke‐induced acute lung injury (ISALI) is lacking. Aerosolized delivery of tissue plasminogen activator (tPA) is confounded by airway bleeding; single‐chain urokinase plasminogen activator (...

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Publicado en:Clin Transl Med
Autores principales: Wolfson, Marla R., Enkhbaatar, Perenlei, Fukuda, Satoshi, Nelson, Christina L., Williams, Robert O., Surasarang, Soraya Hengsawas, Sahakijpijarn, Sawittree, Calendo, Gennaro, Komissarov, Andrey A., Florova, Galina, Sarva, Krishna, Idell, Steven I., Shaffer, Thomas H.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7240845/
https://ncbi.nlm.nih.gov/pubmed/32508014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ctm2.26
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