Orthologous proteins of experimental de- and remyelination are differentially regulated in the CSF proteome of multiple sclerosis subtypes

OBJECTIVE: Here, we applied a multi-omics approach (i) to examine molecular pathways related to de- and remyelination in multiple sclerosis (MS) lesions; and (ii) to translate these findings to the CSF proteome in order to identify molecules that are differentially expressed among MS subtypes. METHO...

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Bibliographic Details
Published in:PLoS One
Main Authors: Martin, Nellie A., Nawrocki, Arkadiusz, Molnar, Viktor, Elkjaer, Maria L., Thygesen, Eva K., Palkovits, Miklos, Acs, Peter, Sejbaek, Tobias, Nielsen, Helle H., Hegedus, Zoltan, Sellebjerg, Finn, Molnar, Tihamer, Barbosa, Eudes G. V., Alcaraz, Nicolas, Gallyas, Ferenc, Svenningsen, Asa F., Baumbach, Jan, Lassmann, Hans, Larsen, Martin R., Illes, Zsolt
Format: Artigo
Language:Inglês
Published: Public Library of Science 2018
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6095600/
https://ncbi.nlm.nih.gov/pubmed/30114292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0202530
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