CSF proteome in multiple sclerosis subtypes related to brain lesion transcriptomes

To identify markers in the CSF of multiple sclerosis (MS) subtypes, we used a two-step proteomic approach: (i) Discovery proteomics compared 169 pooled CSF from MS subtypes and inflammatory/degenerative CNS diseases (NMO spectrum and Alzheimer disease) and healthy controls. (ii) Next, 299 proteins s...

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Published in:Sci Rep
Main Authors: Elkjaer, Maria L., Nawrocki, Arkadiusz, Kacprowski, Tim, Lassen, Pernille, Simonsen, Anja Hviid, Marignier, Romain, Sejbaek, Tobias, Nielsen, Helle H., Wermuth, Lene, Rashid, Alyaa Yakut, Høgh, Peter, Sellebjerg, Finn, Reynolds, Richard, Baumbach, Jan, Larsen, Martin R., Illes, Zsolt
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7892884/
https://ncbi.nlm.nih.gov/pubmed/33603109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83591-5
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