Pre-clinical evaluation of quinoxaline-derived chalcones in tuberculosis

New effective compounds for tuberculosis treatment are needed. This study evaluated the effects of a series of quinoxaline-derived chalcones against laboratorial strains and clinical isolates of M. tuberculosis. Six molecules, namely N5, N9, N10, N15, N16, and N23 inhibited the growth of the M. tube...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Muradás, Thaís C., Abbadi, Bruno L., Villela, Anne D., Macchi, Fernanda S., Bergo, Pedro F., de Freitas, Talita F., Sperotto, Nathalia D. M., Timmers, Luis F. S. M., Norberto de Souza, Osmar, Picada, Jaqueline N., Fachini, Jean, da Silva, Juliana Bondan, de Albuquerque, Nayara C. P., Habenschus, Maísa D., Carrão, Daniel B., Rocha, Bruno A., Barbosa Junior, Fernando, de Oliveira, Anderson R. M., Mascarello, Alessandra, Neuenfeldf, Patrícia, Nunes, Ricardo J., Morbidoni, Héctor R., Campos, Maria M., Basso, Luiz A., Rodrigues-Junior, Valnês S.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6095594/
https://ncbi.nlm.nih.gov/pubmed/30114296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0202568
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