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Mechanisms underlying the antiproliferative effects of a series of quinoxaline-derived chalcones
The present study aimed to characterize the effects of quinoxaline-derived chalcones, designed on the basis of the selective PI3Kγ inhibitor AS605240, in oral cancer cells. Three lead compounds, namely N9, N17 and N23, were selected from a series of 20 quinoxaline-derived chalcones, based on an init...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5696528/ https://ncbi.nlm.nih.gov/pubmed/29158524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16199-3 |
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