Exploring causality in the association between circulating 25-hydroxyvitamin D and colorectal cancer risk: a large Mendelian randomisation study

BACKGROUND: Whilst observational studies establish that lower plasma 25-hydroxyvitamin D (25-OHD) levels are associated with higher risk of colorectal cancer (CRC), establishing causality has proven challenging. Since vitamin D is modifiable, these observations have substantial clinical and public h...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:BMC Med
Κύριοι συγγραφείς: He, Yazhou, Timofeeva, Maria, Farrington, Susan M., Vaughan-Shaw, Peter, Svinti, Victoria, Walker, Marion, Zgaga, Lina, Meng, Xiangrui, Li, Xue, Spiliopoulou, Athina, Jiang, Xia, Hyppönen, Elina, Kraft, Peter, Kiel, Douglas P., Hayward, Caroline, Campbell, Archie, Porteous, David, Vucic, Katarina, Kirac, Iva, Filipovic, Masa, Harris, Sarah E., Deary, Ian J., Houlston, Richard, Tomlinson, Ian P., Campbell, Harry, Theodoratou, Evropi, Dunlop, Malcolm G.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: BioMed Central 2018
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6090711/
https://ncbi.nlm.nih.gov/pubmed/30103784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-018-1119-2
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