Exploring causality in the association between circulating 25-hydroxyvitamin D and colorectal cancer risk: a large Mendelian randomisation study

BACKGROUND: Whilst observational studies establish that lower plasma 25-hydroxyvitamin D (25-OHD) levels are associated with higher risk of colorectal cancer (CRC), establishing causality has proven challenging. Since vitamin D is modifiable, these observations have substantial clinical and public h...

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Detalhes bibliográficos
Publicado no:BMC Med
Main Authors: He, Yazhou, Timofeeva, Maria, Farrington, Susan M., Vaughan-Shaw, Peter, Svinti, Victoria, Walker, Marion, Zgaga, Lina, Meng, Xiangrui, Li, Xue, Spiliopoulou, Athina, Jiang, Xia, Hyppönen, Elina, Kraft, Peter, Kiel, Douglas P., Hayward, Caroline, Campbell, Archie, Porteous, David, Vucic, Katarina, Kirac, Iva, Filipovic, Masa, Harris, Sarah E., Deary, Ian J., Houlston, Richard, Tomlinson, Ian P., Campbell, Harry, Theodoratou, Evropi, Dunlop, Malcolm G.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6090711/
https://ncbi.nlm.nih.gov/pubmed/30103784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-018-1119-2
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