Genetically determined serum urate levels and cardiovascular and other diseases in UK Biobank cohort: A phenome-wide mendelian randomization study

BACKGROUND: The role of urate in cardiovascular diseases (CVDs) has been extensively investigated in observational studies; however, the extent of any causal effect remains unclear, making it difficult to evaluate its clinical relevance. METHODS AND FINDINGS: A phenome-wide association study (PheWAS...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Med
Prif Awduron: Li, Xue, Meng, Xiangrui, He, Yazhou, Spiliopoulou, Athina, Timofeeva, Maria, Wei, Wei-Qi, Gifford, Aliya, Yang, Tian, Varley, Tim, Tzoulaki, Ioanna, Joshi, Peter, Denny, Joshua C., Mckeigue, Paul, Campbell, Harry, Theodoratou, Evropi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2019
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6799886/
https://ncbi.nlm.nih.gov/pubmed/31626644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1002937
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