Asthmatic bronchial epithelial cells promote the establishment of a Hyaluronan-enriched, leukocyte-adhesive extracellular matrix by lung fibroblasts

BACKGROUND: Airway inflammation is a hallmark of asthma. Alterations in extracellular matrix (ECM) hyaluronan (HA) content have been shown to modulate the recruitment and retention of inflammatory cells. Bronchial epithelial cells (BECs) regulate the activity of human lung fibroblasts (HLFs); howeve...

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Publicado no:Respir Res
Main Authors: Reeves, Stephen R., Kang, Inkyung, Chan, Christina K., Barrow, Kaitlyn A., Kolstad, Tessa K., White, Maria P., Ziegler, Steven F., Wight, Thomas N., Debley, Jason S.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6090698/
https://ncbi.nlm.nih.gov/pubmed/30071849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-018-0849-1
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