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Asthmatic bronchial epithelial cells promote the establishment of a Hyaluronan-enriched, leukocyte-adhesive extracellular matrix by lung fibroblasts

BACKGROUND: Airway inflammation is a hallmark of asthma. Alterations in extracellular matrix (ECM) hyaluronan (HA) content have been shown to modulate the recruitment and retention of inflammatory cells. Bronchial epithelial cells (BECs) regulate the activity of human lung fibroblasts (HLFs); howeve...

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Publicat a:Respir Res
Autors principals: Reeves, Stephen R., Kang, Inkyung, Chan, Christina K., Barrow, Kaitlyn A., Kolstad, Tessa K., White, Maria P., Ziegler, Steven F., Wight, Thomas N., Debley, Jason S.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6090698/
https://ncbi.nlm.nih.gov/pubmed/30071849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-018-0849-1
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