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Asthmatic airway epithelial cells differentially regulate fibroblast expression of extracellular matrix components

BACKGROUND: Airway remodeling may explain lung function decline among asthmatic children. Extracellular matrix (ECM) deposition by human lung fibroblasts (HLFs) is implicated in airway remodeling. Airway epithelial cell (AEC) signaling may regulate HLF ECM expression. OBJECTIVES: Determine whether A...

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Bibliografiske detaljer
Main Authors: Reeves, Stephen R., Kolstad, Tessa, Lien, Tin-Yu, Elliott, Molly, Ziegler, Steven F., Wight, Thomas N., Debley, Jason S.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149938/
https://ncbi.nlm.nih.gov/pubmed/24875618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2014.04.007
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