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Asthmatic airway epithelial cells differentially regulate fibroblast expression of extracellular matrix components

BACKGROUND: Airway remodeling may explain lung function decline among asthmatic children. Extracellular matrix (ECM) deposition by human lung fibroblasts (HLFs) is implicated in airway remodeling. Airway epithelial cell (AEC) signaling may regulate HLF ECM expression. OBJECTIVES: Determine whether A...

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Bibliographic Details
Main Authors: Reeves, Stephen R., Kolstad, Tessa, Lien, Tin-Yu, Elliott, Molly, Ziegler, Steven F., Wight, Thomas N., Debley, Jason S.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149938/
https://ncbi.nlm.nih.gov/pubmed/24875618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2014.04.007
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