Fibroblast gene expression following asthmatic bronchial epithelial cell conditioning correlates with epithelial donor lung function and exacerbation history

Airway remodeling may contribute to decreased lung function in asthmatic children. Bronchial epithelial cells (BECs) may regulate fibroblast expression of extracellular matrix (ECM) constituents and fibroblast-to-myofibroblast transition (FMT). Our objective was to determine if human lung fibroblast...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Reeves, Stephen R., Barrow, Kaitlyn A., Kolstad, Tessa K., White, Maria P., Rich, Lucille M., Wight, Thomas N., Debley, Jason S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6202408/
https://ncbi.nlm.nih.gov/pubmed/30361541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-34021-6
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