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Respiratory Syncytial Virus Infection of Human Lung Fibroblasts Induces a Hyaluronan-Enriched Extracellular Matrix That Binds Mast Cells and Enhances Expression of Mast Cell Proteases

Human lung fibroblasts (HLFs) treated with the viral mimetic polyinosine-polycytidylic acid (poly I:C) form an extracellular matrix (ECM) enriched in hyaluronan (HA) that avidly binds monocytes and lymphocytes. Mast cells are important innate immune cells in both asthma and acute respiratory infecti...

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Bibliografski detalji
Izdano u:Front Immunol
Glavni autori: Reeves, Stephen R., Barrow, Kaitlyn A., Rich, Lucille M., White, Maria P., Shubin, Nicholas J., Chan, Christina K., Kang, Inkyung, Ziegler, Steven F., Piliponsky, Adrian M., Wight, Thomas N., Debley, Jason S.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6997473/
https://ncbi.nlm.nih.gov/pubmed/32047499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.03159
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