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PARP2 mediates branched poly ADP-ribosylation in response to DNA damage

Poly(ADP-ribosyl)ation (PARylation) is a posttranslational modification involved in multiple biological processes, including DNA damage repair. This modification is catalyzed by poly(ADP-ribose) polymerase (PARP) family of enzymes. PARylation is composed of both linear and branched polymers of poly(...

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Publicat a:Nat Commun
Autors principals: Chen, Qian, Kassab, Muzaffer Ahmad, Dantzer, Françoise, Yu, Xiaochun
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089979/
https://ncbi.nlm.nih.gov/pubmed/30104678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05588-5
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