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Physiologically‐based pharmacokinetic model of vaginally administered dapivirine ring and film formulations
AIMS: A physiologically‐based pharmacokinetic (PBPK) model of the vaginal space was developed with the aim of predicting concentrations in the vaginal and cervical space. These predictions can be used to optimize the probability of success of vaginally administered dapivirine (DPV) for HIV preventio...
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| 發表在: | Br J Clin Pharmacol |
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| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
John Wiley and Sons Inc.
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6089833/ https://ncbi.nlm.nih.gov/pubmed/29714824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13625 |
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