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Physiologically‐based pharmacokinetic model of vaginally administered dapivirine ring and film formulations

AIMS: A physiologically‐based pharmacokinetic (PBPK) model of the vaginal space was developed with the aim of predicting concentrations in the vaginal and cervical space. These predictions can be used to optimize the probability of success of vaginally administered dapivirine (DPV) for HIV preventio...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Kay, Katherine, Shah, Dhaval K., Rohan, Lisa, Bies, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089833/
https://ncbi.nlm.nih.gov/pubmed/29714824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13625
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