Gestational changes in buprenorphine exposure: A physiologically‐based pharmacokinetic analysis

AIMS: Buprenorphine (BUP) is approved by the US Food and Drug Administration for the treatment of opioid addiction. The current dosing regimen of BUP in pregnant women is based on recommendations designed for nonpregnant adults. However, physiological changes during pregnancy may alter BUP exposure...

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Bibliografiske detaljer
Udgivet i:Br J Clin Pharmacol
Main Authors: Zhang, Hongfei, Kalluri, Hari V., Bastian, Jaime R., Chen, Huijun, Alshabi, Ali, Caritis, Steve N., Venkataramanan, Raman
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089832/
https://ncbi.nlm.nih.gov/pubmed/29873094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13642
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