Population pharmacokinetics of 17α‐hydroxyprogesterone caproate in singleton gestation

AIMS: 17α‐hydroxyprogesterone caproate (17‐OHPC) reduces the rate of preterm birth in women with a prior preterm birth. Limited data exist on the pharmacokinetics (PK) of 17‐OHPC or the plasma concentrations achieved during therapy. In this study, we evaluated the population PK of 17‐OHPC in pregnan...

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Udgivet i:Br J Clin Pharmacol
Main Authors: Sharma, Shringi, Caritis, Steve, Hankins, Gary, Miodovnik, Menachem, Hebert, Mary F., Mattison, Don, Venkataramanan, Raman
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Drugs in Pregnancy and Lactation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137834/
https://ncbi.nlm.nih.gov/pubmed/27133963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12990
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