Population pharmacokinetics of 17α‐hydroxyprogesterone caproate in singleton gestation

AIMS: 17α‐hydroxyprogesterone caproate (17‐OHPC) reduces the rate of preterm birth in women with a prior preterm birth. Limited data exist on the pharmacokinetics (PK) of 17‐OHPC or the plasma concentrations achieved during therapy. In this study, we evaluated the population PK of 17‐OHPC in pregnan...

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Veröffentlicht in:Br J Clin Pharmacol
Hauptverfasser: Sharma, Shringi, Caritis, Steve, Hankins, Gary, Miodovnik, Menachem, Hebert, Mary F., Mattison, Don, Venkataramanan, Raman
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2016
Schlagworte:
Drugs in Pregnancy and Lactation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137834/
https://ncbi.nlm.nih.gov/pubmed/27133963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12990
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