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Gestational changes in buprenorphine exposure: A physiologically‐based pharmacokinetic analysis

AIMS: Buprenorphine (BUP) is approved by the US Food and Drug Administration for the treatment of opioid addiction. The current dosing regimen of BUP in pregnant women is based on recommendations designed for nonpregnant adults. However, physiological changes during pregnancy may alter BUP exposure...

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書目詳細資料
發表在:Br J Clin Pharmacol
Main Authors: Zhang, Hongfei, Kalluri, Hari V., Bastian, Jaime R., Chen, Huijun, Alshabi, Ali, Caritis, Steve N., Venkataramanan, Raman
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089832/
https://ncbi.nlm.nih.gov/pubmed/29873094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13642
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