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Interleukin-1 in Monocyte Activation Phenotypes in Systemic Juvenile Idiopathic Arthritis: observations from a clinical trial of rilonacept, an interleukin-1 inhibitor
Systemic juvenile idiopathic arthritis (sJIA) is a childhood rheumatic disease of unknown origin. Dysregulated innate immunity is implicated in disease pathology. We investigated if IL-1 inhibition affects circulating cytokines and monocyte gene expression. CD14+ monocytes from patients in the RAPPO...
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| Gepubliceerd in: | Clin Immunol |
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| Hoofdauteurs: | , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6089654/ https://ncbi.nlm.nih.gov/pubmed/29928998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2018.06.005 |
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