Altered signaling in systemic juvenile idiopathic arthritis monocytes

Systemic juvenile idiopathic arthritis (sJIA) is characterized by systemic inflammation and arthritis. Monocytes are implicated in sJIA pathogenesis, but their role in disease is unclear. The response of sJIA monocytes to IFN may be dysregulated. We examined intracellular signaling in response to IF...

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Pubblicato in:Clin Immunol
Autori principali: Macaubas, Claudia, Wong, Elizabeth, Zhang, Yujuan, Nguyen, Khoa D., Lee, Justin, Milojevic, Diana, Shenoi, Susan, Stevens, Anne M., Ilowite, Norman, Saper, Vivian, Lee, Tzielan, Mellins, Elizabeth D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4753112/
https://ncbi.nlm.nih.gov/pubmed/26747737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2015.12.011
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