Interleukin-1 in Monocyte Activation Phenotypes in Systemic Juvenile Idiopathic Arthritis: observations from a clinical trial of rilonacept, an interleukin-1 inhibitor

Systemic juvenile idiopathic arthritis (sJIA) is a childhood rheumatic disease of unknown origin. Dysregulated innate immunity is implicated in disease pathology. We investigated if IL-1 inhibition affects circulating cytokines and monocyte gene expression. CD14+ monocytes from patients in the RAPPO...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Clin Immunol
Главные авторы: Zhang, Yujuan, Gupta, Saloni, Ilstad-Minnihan, Alexandra, Ayyangar, Sashi, Hay, Arielle D., Pascual, Virginia, Ilowite, Norman T., Macaubas, Claudia, Mellins, Elizabeth D
Формат: Artigo
Язык:Inglês
Опубликовано: 2018
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089654/
https://ncbi.nlm.nih.gov/pubmed/29928998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2018.06.005
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы