The RAndomized Placebo Phase Study Of Rilonacept in the Treatment of Systemic Juvenile Idiopathic Arthritis (RAPPORT)

BACKGROUND: Interleukin-1 plays a pivotal role in in the pathogenesis of systemic juvenile idiopathic arthritis (sJIA). We assessed the efficacy and safety of rilonacept (IL-1 trap), an IL-1 inhibitor, in a randomized, double-blind, placebo-controlled trial. METHODS: An initial 4-week double-blind p...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Arthritis Rheumatol
Egile Nagusiak: Ilowite, Norman T., Prather, Kristi, Lokhnygina, Yuliya, Schanberg, Laura E., Elder, Melissa, Milojevic, Diana, Verbsky, James W., Spalding, Steven J., Kimura, Yukiko, Imundo, Lisa F., Punaro, Marilynn G., Sherry, David D., Tarvin, Stacey E., Zemel, Lawrence S., Birmingham, James D., Gottlieb, Beth S., Miller, Michael L., O'Neil, Kathleen, Ruth, Natasha M., Wallace, Carol A., Singer, Nora G., Sandborg, Christy I.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314719/
https://ncbi.nlm.nih.gov/pubmed/24839206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38699
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