The RAndomized Placebo Phase Study Of Rilonacept in the Treatment of Systemic Juvenile Idiopathic Arthritis (RAPPORT)

BACKGROUND: Interleukin-1 plays a pivotal role in in the pathogenesis of systemic juvenile idiopathic arthritis (sJIA). We assessed the efficacy and safety of rilonacept (IL-1 trap), an IL-1 inhibitor, in a randomized, double-blind, placebo-controlled trial. METHODS: An initial 4-week double-blind p...

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Detalhes bibliográficos
Publicado no:Arthritis Rheumatol
Main Authors: Ilowite, Norman T., Prather, Kristi, Lokhnygina, Yuliya, Schanberg, Laura E., Elder, Melissa, Milojevic, Diana, Verbsky, James W., Spalding, Steven J., Kimura, Yukiko, Imundo, Lisa F., Punaro, Marilynn G., Sherry, David D., Tarvin, Stacey E., Zemel, Lawrence S., Birmingham, James D., Gottlieb, Beth S., Miller, Michael L., O'Neil, Kathleen, Ruth, Natasha M., Wallace, Carol A., Singer, Nora G., Sandborg, Christy I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314719/
https://ncbi.nlm.nih.gov/pubmed/24839206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38699
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