Selinexor reduces the expression of DNA damage repair proteins and sensitizes cancer cells to DNA damaging agents

INTRODUCTION: The goal of this study was to examine the effects of selinexor, an inhibitor of exportin-1 mediated nuclear export, on DNA damage repair and to evaluate the cytotoxic effects of selinexor in combination with DNA damaging agents (DDAs) in cancer cells. RESULTS: Selinexor reduced the exp...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Kashyap, Trinayan, Argueta, Christian, Unger, Thaddeus, Klebanov, Boris, Debler, Sophia, Senapedis, William, Crochiere, Marsha L., Lee, Margaret S., Kauffman, Michael, Shacham, Sharon, Landesman, Yosef
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2018
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089403/
https://ncbi.nlm.nih.gov/pubmed/30112106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25637
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items