Lineage tracing aged mouse kidneys shows lower number of cells of renin lineage and reduced responsiveness to RAAS inhibition

Blocking the renin-angiotensin-aldosterone system (RAAS) remains a mainstay of therapy in hypertension and glomerular diseases. With the population aging, our understanding of renin-producing cells in kidneys with advanced age is more critical than ever. Accordingly, we administered tamoxifen to Ren...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Am J Physiol Renal Physiol
Egile Nagusiak: Hamatani, Hiroko, Eng, Diana G., Kaverina, Natalya V., Gross, Kenneth W., Freedman, Benjamin S., Pippin, Jeffrey W., Shankland, Stuart J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2018
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6087792/
https://ncbi.nlm.nih.gov/pubmed/29412700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00570.2017
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